Catalogue
Research peptides2 specifications

Epithalon

COA on request

Epithalon is an anti-aging peptide that activates telomerase to protect and extend telomeres, supporting cellular repair and healthier aging. It also regulates melatonin production to improve sleep quality, while boosting immune function and antioxidant defense—offering a well-rounded approach to longevity support.

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ET10
Pack
10 mg x 10 vials
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Purity≥99%Estimated delivery: within one week after the order is placed.
COA is available on request

COA files are available in the document library; additional batch-specific documentation can be requested with your inquiry. Each batch is tested with HPLC purity analysis (≥99%). For MSDS or detailed storage protocols, please contact our sales team.

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DocumentationCOA available on request

Research effects

Epithalon (also known as Epitalon) is a synthetic tetrapeptide (Ala-Glu-Asp-Gly) that demonstrates unique research value in lifespan extension, circadian rhythm regulation, and overall health enhancement. Preclinical studies have shown that Epithalon extends the lifespan of various experimental animals and delays age-related physiological decline. In human studies, it has been observed to restore the nocturnal secretion rhythm of melatonin, improve sleep quality, and enhance immune system function. Additionally, Epithalon exhibits potential antioxidant and antitumor activities, helping to protect cells from oxidative damage. Users also report positive effects including improved skin elasticity, increased energy levels, and enhanced overall vitality.

Research mechanism

The core mechanism of Epithalon is closely associated with its regulation of telomerase activity. It promotes telomere maintenance and elongation by upregulating telomerase reverse transcriptase (TERT) expression, thereby delaying replicative senescence at the cellular level. Concurrently, Epithalon acts on the pineal gland, restoring and stabilizing the circadian rhythmic secretion of melatonin through activation of G protein-coupled receptor (GPCR) signaling pathways, thereby coordinating the functional balance of the hypothalamic-pituitary-adrenal (HPA) axis and the immune system. Furthermore, Epithalon possesses antioxidant properties that reduce intracellular reactive oxygen species (ROS) levels and regulate the expression of apoptosis-related proteins including Bcl-2 and Bax, enhancing cellular resistance to stress.

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Store unopened material in its original sealed packaging, protected from light, moisture, and repeated temperature changes. Follow the product label and batch document for the exact storage temperature. After opening or preparation, use only a validated laboratory storage protocol.

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ET1010 mg x 10 vials