Research effects
Ipamorelin is a selective growth hormone secretagogue receptor (GHS-R) agonist that demonstrates potent efficacy in promoting endogenous growth hormone (GH) release while gaining attention for its high selectivity.
Catalogue
Research peptides2 specifications
Ipamorelin
COA on requestIpamorelin is a synthetic pentapeptide and selective ghrelin-receptor research agonist. The listed vial strengths are consolidated under a single product family.
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Purity≥98%Estimated delivery: within one week after the order is placed.
COA is available on request
COA files are available in the document library; additional batch-specific documentation can be requested with your inquiry. Each batch is tested with HPLC purity analysis (≥98%). For MSDS or detailed storage protocols, please contact our sales team.
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DocumentationCOA available on request
Efficacy
Users commonly report this peptide effectively increases muscle mass, reduces body fat, improves sleep quality, and accelerates post-exercise recovery. Compared to many other GHS peptides, Ipamorelin produces virtually no elevation of prolactin or cortisol levels within effective dose ranges, making it regarded as a "clean" and mild GH secretagogue. Furthermore, Ipamorelin exhibits significant synergistic effects when combined with GHRH analogues such as CJC-1295 NO DAC, making it a common component in growth hormone secretagogue combination protocols.
Research mechanism
Ipamorelin acts by binding to GHS-R1a receptors in the pituitary and hypothalamus, mimicking ghrelin's mode of action to activate the phospholipase C signaling pathway and increase intracellular calcium concentration, thereby stimulating pulsatile GH release. Its structural design confers high selectivity for GHS-R1a, serving as the molecular basis for its minimal impact on prolactin and cortisol. Unlike ghrelin, Ipamorelin does not stimulate gastric acid secretion or gastric motility, nor does it significantly affect appetite, contributing to better tolerability in long-term use. Its GH-releasing effect peaks approximately 30-60 minutes post-injection, with a half-life of approximately 2 hours, making it suitable for multiple daily dosing protocols.
Product details
Key identity and handling information for the selected research material.
Material identity
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Storage guidance
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