Proteins and hormones1 specification

HMG

Name: HMG
Brand: SUN Peptides
SKU: G75

COA on request

HMG (Human Menopausal Gonadotropin): A hormone preparation that supports fertility and hormonal balance. It contains both FSH (follicle-stimulating hormone) and LH (luteinizing hormone) — two key hormones that play a direct role in reproductive function. In women, it helps stimulate egg development and ovulation. In men, it supports sperm production and testosterone synthesis. It's often used in clinical fertility treatments and hormone support protocols.

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Selected SKU: G75
Pack: 75 IU x 10 vials
Status: Available for inquiry

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Purity≥98%Estimated delivery: within one week after the order is placed.

COA is available on request

COA files are available in the document library; additional batch-specific documentation can be requested with your inquiry. Each batch is tested with HPLC purity analysis (≥98%). For MSDS or detailed storage protocols, please contact our sales team.

Order formatOne box accepted

DeliveryWithin one week after order

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DocumentationCOA available on request

Research effects

Human menopausal gonadotropin (HMG) is a gonadotropin preparation extracted from the urine of postmenopausal women, containing equal follicle-stimulating hormone (FSH) and luteinizing hormone (LH) activity. In reproductive medicine, HMG is widely used to induce follicle growth and maturation for treating infertility due to ovulation disorders, and to promote multifollicular development in assisted reproductive technologies (e.g., IVF). In males, HMG is used to stimulate spermatogenesis in treating male infertility resulting from gonadotropin deficiency. Compared to purified FSH preparations, HMG provides more comprehensive support for patients with hypothalamic-pituitary axis dysfunction due to its LH activity, contributing to improved endometrial receptivity and higher pregnancy success rates.

Research mechanism

HMG activates specific receptors in the ovaries and testes through its FSH and LH components. The FSH component binds to FSH receptors on ovarian granulosa cells or testicular Sertoli cells, stimulating the cAMP/PKA signaling pathway to promote follicle growth and estradiol secretion, or support spermatogenesis. The LH-active component binds to LHCG receptors on theca cells (in females) or testicular Leydig cells (in males), stimulating androgen synthesis (including testosterone and androstenedione), which are then aromatized to estrogens by granulosa cells, synergistically promoting final follicular maturation and ovulation. The synergistic action of both hormones ensures complete gonadal axis activation, providing a more physiological gonadotropin support compared to FSH stimulation alone.

Product details

Key identity and handling information for the selected research material.

Material identity

FSH/LH activity ratio, source, unit definition, purification method, excipients, and storage conditions should be verified for each lot.

Storage guidance

Store unopened material in its original sealed packaging, protected from light, moisture, and repeated temperature changes. Follow the product label and batch document for the exact storage temperature. After opening or preparation, use only a validated laboratory storage protocol.

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G7575 IU x 10 vials

HMG